Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.68 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.53 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294100 | 0.94 | BCL9 (0.76) | BCL9CTNNB1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL27716579 | 0.92 | BCL9 (0.73) | BCL9CTNNB1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL10727099 | 0.85 | MAPT (0.70) | BCL9CTNNB1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL2738370 | 0.83 | BCL9 (0.66) | BCL9CTNNB1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL10722598 | 0.81 | MAPT (0.65) | BCL9CTNNB1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL10727729 | 0.81 | MAPT (0.65) | BCL9CTNNB1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL133257 | 0.81 | BCL9 (1.00) | BCL9CTNNB1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL20467771 | 0.80 | HTR2A (0.71) | BCL9CTNNB1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL2294260 | 0.80 | BCL9 (0.66) | BCL9CTNNB1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL9967879 | 0.80 | BCL9 (0.70) | BCL9CTNNB1SMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049860-B1 | PROCESS FOR THE PREPARATION OF REACTIVE THYROID GLAND HORMONES T3 AND T4 DERIVATIVES THAT ARE CAPABLE OF COUPLING, AND THEIR USE | Roche Diagnostics GmbH (DE) | 1984-10-03 | — | — | EP | disclosed |
| EP-0049860-A1 | Process for the preparation of reactive thyroid gland hormones T3 and T4 derivatives that are capable of coupling, and their use | Roche Diagnostics GmbH (DE) | 1982-04-21 | — | — | EP | disclosed |