SCHEMBL133257

SCHEMBL133257

CCCC(=O)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 1.00
CTNNB1 P35222 1/20 1.00
MGLL Q99685 2/20 0.58
KMT2A Q03164 5/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
MAPT P10636 4/20 0.57
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
GAA P10253 1/20 0.57
PTPN7 P35236 1/20 0.52
PTPN12 Q05209 1/20 0.52
PTPN22 Q9Y2R2 1/20 0.52
ALDH1A1 P00352 3/20 0.49
HSD17B10 Q99714 2/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
PKM P14618 1/20 0.49
LMNA P02545 2/20 0.49
HTT P42858 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26111924 0.98 BCL9 (0.97) BCL9CTNNB1MGLLKMT2ASMN1; SMN2
Butyric Acid SCHEMBL2307779 0.94 BCL9 (0.88) BCL9CTNNB1MGLLKMT2ASMN1; SMN2
SCHEMBL28215337 0.91 BCL9 (0.83) BCL9CTNNB1MGLLKMT2ASMN1; SMN2
SCHEMBL10728358 0.91 BCL9 (0.83) BCL9CTNNB1MGLLKMT2ASMN1; SMN2
SCHEMBL27348135 0.91 BCL9 (0.83) BCL9CTNNB1MGLLKMT2ASMN1; SMN2
SCHEMBL30694347 0.91 BCL9 (0.83) BCL9CTNNB1MGLLKMT2ASMN1; SMN2
SCHEMBL828974 0.90 BCL9 (0.82) BCL9CTNNB1MGLLKMT2ASMN1; SMN2
SCHEMBL957930 0.90 BCL9 (0.81) BCL9CTNNB1MGLLKMT2ASMN1; SMN2
SCHEMBL1400174 0.89 BCL9 (0.80) BCL9CTNNB1MGLLKMT2ASMN1; SMN2
P-Nitrophenol SCHEMBL28859114 0.89 BCL9 (0.79) BCL9CTNNB1MGLLKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1890 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559735-B2 Device for detecting organophosphates PLANTVAX, INC. (US) 2026-02-24 US claimed
CN-119286820-A Novel esterase and encoding gene and novel application thereof 常州大学 2025-01-10 CN claimed
EP-3696264-B1 COMPOSITIONS AND METHODS COMPRISING A LIPOLYTIC ENZYME VARIANT DANISCO US INC (US) 2023-06-28 EP claimed
CN-111057691-B Novel GDSL family lipid hydrolase EII-3 and encoding gene and application thereof 自然资源部第二海洋研究所 2023-04-28 CN claimed
CN-108251401-B Lipase and application thereof 丰益(上海)生物技术研发中心有限公司 2022-11-04 CN claimed
CN-107189955-B Novel deep-sea thermostable alkaline esterase and application thereof 自然资源部第二海洋研究所 2022-07-15 CN claimed
CN-114736887-A Use of carboxylesterase 上海威高医疗技术发展有限公司 2022-07-12 CN claimed
CN-114694776-A Refining of pueraria flower isoflavone and research method of lipid-lowering effect thereof 长春职业技术学院 2022-07-01 CN claimed
CN-110004125-B Novel alkali-resistant and organic solvent-resistant esterase from marine bacteria and application thereof 自然资源部第二海洋研究所 2022-05-20 CN claimed
CN-113087833-B Polymer-supported artificial catalysis triad catalyst and preparation method and application thereof 湖北大学 2022-04-01 CN claimed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 EP claimed
EP-0897942-B1 A method of crosslinking collagen-based material and bioprosthetic devices produced therefrom MEDTRONIC INC (US) 2004-03-10 EP claimed
US-6166184-A Process for making a bioprosthetic device MEDTRONIC INC. (US) 2000-12-26 US claimed
EP-0897942-A1 A method of crosslinking collagen-based material and bioprosthetic devices produced therefrom MEDTRONIC, INC. (US) 1999-02-24 EP claimed
CN-1161962-A Sulphonic-acid-amide derivative KONO PHARMACEUTICAL IND K K (JP) 1997-10-15 CN claimed
US-5188937-A Binding of signal antibody to antigen BECTON, DICKINSON AND COMPANY (US) 1993-02-23 US claimed
US-5164515-A Chemical compounds WENDSTONE CHEMICALS PLC (GB) 1992-11-17 US claimed
EP-0268452-B1 NOVEL HYDROLASE AND METHOD OF PRODUCTION GENENCOR, INC. (US) 1992-01-22 EP claimed
EP-0268452-A2 Novel hydrolase and method of production GENENCOR, INC. (US) 1988-05-25 EP claimed
EP-0239354-A2 2,2-Dinitrophenylethane derivatives and their application as protecting compounds Wendstone Chemicals P.L.C. (GB) 1987-09-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559735-B2 Device for detecting organophosphates BCHE, LIPE, ACHE BCL9 2500/4885CTNNB1 3981/4885MGLL 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.