Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091577 | 0.85 | ABL1 (0.42) | ABL1ALDH1A1KMT2AUSP2CYP1A2 | |
| SCHEMBL11091746 | 0.83 | ABL1 (0.49) | ABL1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL11060490 | 0.81 | ABL1 (0.48) | ABL1ALDH1A1KMT2AMEN1MAOB | |
| SCHEMBL11057637 | 0.80 | ABL1 (0.74) | ABL1ALDH1A1KMT2AMEN1MAOB | |
| SCHEMBL11094011 | 0.75 | ALOX5 (0.43) | ABL1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7721894 | 0.73 | BRD4 (0.39) | ABL1ALDH1A1KMT2AMEN1MAOB | |
| SCHEMBL10918588 | 0.72 | ALOX5 (0.45) | ABL1ALDH1A1CYP1A2LMNAMAPT | |
| SCHEMBL11095686 | 0.68 | ABL1 (0.46) | ABL1ALDH1A1KMT2AUSP2CYP1A2 | |
| SCHEMBL11057701 | 0.67 | ABL1 (0.48) | ABL1KMT2ACYP1A2CYP2D6MAPT | |
| SCHEMBL11058383 | 0.67 | ABL1 (0.42) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448973-A | ANTIINFLAMMATORY, ANALGESIC AGENTS; BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-15 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |