Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10836755 | 0.85 | ABL1 (0.39) | ABL1PRKCZALDH1A1PDE5AMEN1 | |
| SCHEMBL11091186 | 0.83 | ABL1 (0.43) | ABL1PRKCZALDH1A1LMNABRD4 | |
| SCHEMBL11092462 | 0.83 | ABL1 (0.49) | ABL1PRKCZALDH1A1LMNABRD4 | |
| SCHEMBL11057742 | 0.79 | ABL1 (0.49) | ABL1PRKCZALDH1A1LMNABRD4 | |
| SCHEMBL11093164 | 0.78 | ABL1 (0.45) | ABL1PRKCZBRD4PDE5A | |
| SCHEMBL11061067 | 0.77 | ABL1 (0.74) | ABL1PRKCZALDH1A1LMNAPDE5A | |
| SCHEMBL10838522 | 0.75 | ABL1 (0.57) | ABL1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL907974 | 0.73 | PRKCZ (0.41) | ABL1PRKCZBRD4PDE5A | |
| SCHEMBL11061324 | 0.73 | ABL1 (0.55) | ABL1PRKCZALDH1A1LMNAPDE5A | |
| Hydrochloric Acid SCHEMBL10656738 | 0.72 | PRKCZ (0.40) | ABL1PRKCZBRD4PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448973-A | ANTIINFLAMMATORY, ANALGESIC AGENTS; BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-15 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |