SCHEMBL11096427

SCHEMBL11096427

Cc1ccc(COc2ccc(N)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.67
APP P05067 1/20 0.67
MAPT P10636 3/20 0.66
RAB9A P51151 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
GAA P10253 1/20 0.66
MAOA P21397 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
PARP10 Q53GL7 1/20 0.62
ALDH1A1 P00352 2/20 0.58
MAPK1 P28482 1/20 0.58
TEAD4 Q15561 1/20 0.57
NPC1 O15118 1/20 0.56
CASP3 P42574 1/20 0.56
SENP8 Q96LD8 1/20 0.56
SENP7 Q9BQF6 1/20 0.56
SENP6 Q9GZR1 1/20 0.56
TDP1 Q9NUW8 2/20 0.55
POLB P06746 1/20 0.55
HRH3 Q9Y5N1 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5121663 0.89 MAOB (0.80) MAOBAPPMAPTRAB9ASMN1; SMN2
SCHEMBL762195 0.89 MAOB (0.69) MAOBAPPMAPTRAB9ASMN1; SMN2
SCHEMBL891195 0.89 MAOB (0.69) MAOBAPPMAPTRAB9ASMN1; SMN2
SCHEMBL8929713 0.89 MAOB (0.69) MAOBAPPMAPTRAB9ASMN1; SMN2
SCHEMBL8930213 0.89 MAOB (0.69) MAOBAPPMAPTRAB9ASMN1; SMN2
SCHEMBL31542030 0.89 MAOB (0.80) MAOBAPPMAPTRAB9ASMN1; SMN2
SCHEMBL5370546 0.84 PARP10 (0.65) MAOBAPPMAPTRAB9ASMN1; SMN2
SCHEMBL26317278 0.84 AGXT (0.76) MAOBAPPMAPTRAB9ASMN1; SMN2
SCHEMBL13766361 0.84 MAOB (0.67) MAOBAPPMAPTRAB9ASMN1; SMN2
SCHEMBL8942259 0.84 MAOB (0.70) MAOBAPPMAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115955968-A Carbohydrazone acyldinitrile compounds comprising at least two aryl or heteroaryl groups connected by a novel linker and uses thereof 韩国科学技术研究院 2023-04-11 CN disclosed
EP-3760633-A1 OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF Beijing Scitech-MQ Pharmaceuticals Limited (CN) 2021-01-06 EP disclosed
EP-1551810-B1 DIARYL-SUBSTITUTED CYCLIC UREA DERIVATIVES HAVING AN MCH-MODULATORY EFFECT SANOFI AVENTIS DEUTSCHLAND (DE) 2011-11-30 EP disclosed
EP-0113922-A2 Process for the manufacture of cationic methine dyes BAYER AG (DE) 1984-07-25 EP disclosed
EP-0113920-A2 Process for the manufacture of stable solutions of cationic methine dyes, and their use in spin dyeing BAYER AG (DE) 1984-07-25 EP disclosed
EP-0113921-A2 Process for the manufacture of stable solutions of cationic methine dyes BAYER AG (DE) 1984-07-25 EP disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed