Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103549 | 0.82 | ADRA2A (0.69) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL8051573 | 0.78 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL14856666 | 0.78 | TAAR1 (0.58) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| Hydrochloric Acid SCHEMBL29751822 | 0.77 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL10848795 | 0.75 | L3MBTL1 (0.51) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL4018722 | 0.75 | TAAR1 (0.67) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL11568003 | 0.75 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL1509682 | 0.75 | TAAR1 (0.67) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL6112047 | 0.75 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CTAAR1HTR1A | |
| SCHEMBL2775376 | 0.75 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CTAAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005250-B1 | HYDROXYPROPYL IMIDAZOLES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | BAYER AG (DE) | 1981-08-12 | — | — | EP | claimed |
| EP-0029542-B1 | HYDROXYBUTYL-IMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES NECESSARY FOR THE LATTER AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1984-07-18 | — | — | EP | disclosed |
| EP-0019190-B1 | USE OF HYDROXYALKYL-IMIDAZOLES AS FUNGICIDES | BAYER AG (DE) | 1983-03-30 | — | — | EP | disclosed |
| EP-0031883-B1 | ANTIMICROBIAL AGENT CONTAINING HYDROXY BUTYLIMIDAZOLE DERIVATIVES | BAYER AG (DE) | 1983-03-02 | — | — | EP | disclosed |
| EP-0005250-B1 | HYDROXYPROPYL IMIDAZOLES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | BAYER AG (DE) | 1981-08-12 | — | — | EP | disclosed |
| EP-0031883-A1 | Antimicrobial agent containing hydroxy butylimidazole derivatives | BAYER AG (DE) | 1981-07-15 | — | — | EP | disclosed |
| EP-0029542-A2 | Hydroxybutyl-imidazole derivatives, process for their preparation, intermediates necessary for the latter and their use as fungicides | BAYER AG (DE) | 1981-06-03 | — | — | EP | disclosed |
| EP-0019190-A2 | Use of hydroxyalkyl-imidazoles as fungicides | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
| EP-0005250-A2 | Hydroxypropyl imidazoles, their preparation and medicaments containing them | BAYER AG (DE) | 1979-11-14 | — | — | EP | disclosed |