Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 12/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10968292 | 0.89 | ACE (0.64) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL11066109 | 0.85 | ACE (0.63) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL10938811 | 0.85 | ACE (0.63) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL11065988 | 0.84 | ACE (0.67) | ACELMNA | |
| SCHEMBL683556 | 0.84 | ACE (0.67) | ACELMNA | |
| SCHEMBL11096479 | 0.82 | ACE (0.64) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL10824002 | 0.81 | FFAR2 (0.41) | ACEFFAR2 | |
| SCHEMBL683644 | 0.80 | ACE (0.67) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL11063036 | 0.78 | ACE (0.82) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL10940835 | 0.78 | ACE (0.60) | ACELMNAFFAR2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483861-A | Antihypertensive sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-11-20 | — | — | US | claimed |