Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097229 | 0.81 | ESR1 (0.54) | ACACBMTNR1AMTNR1B | |
| SCHEMBL11686920 | 0.79 | ACACB (0.63) | ACACB | |
| SCHEMBL11100510 | 0.75 | ALDH1A1 (0.45) | — | |
| SCHEMBL27544708 | 0.75 | ALDH1A1 (0.45) | — | |
| SCHEMBL21949349 | 0.74 | ALDH1A1 (0.44) | ACACB | |
| SCHEMBL9319775 | 0.74 | PDE10A (0.39) | — | |
| SCHEMBL11375563 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL8385587 | 0.73 | ACACB (0.56) | ACACBMTNR1AMTNR1B | |
| SCHEMBL11989413 | 0.73 | ACACB (0.56) | ACACBMTNR1AMTNR1B | |
| SCHEMBL8385561 | 0.73 | ACACB (0.56) | ACACBMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019739-B1 | 2-AMINOALKYL-5-PYRIDINOLES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1984-07-18 | — | — | EP | disclosed |
| US-4260619-A | ANTIISCHEMIC | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| EP-0019739-A1 | 2-Aminoalkyl-5-pyridinoles, process for their preparation and pharmaceutical preparations containing them | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |