Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27544708 | 0.81 | ALDH1A1 (0.45) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL11100510 | 0.81 | ALDH1A1 (0.45) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL11375563 | 0.80 | ALDH1A1 (0.44) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL10347409 | 0.79 | TLR4 (0.36) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL10347412 | 0.79 | TLR4 (0.36) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL10347410 | 0.79 | TLR4 (0.36) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL13534998 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTKMT2AALOX15 | |
| SCHEMBL18851549 | 0.77 | MCHR1 (0.43) | ALDH1A1MAPTPDE10AKDM4EALOX15 | |
| SCHEMBL18763952 | 0.77 | NQO1 (0.50) | ALDH1A1LMNAACACBMAPTKMT2A | |
| SCHEMBL10347437 | 0.76 | HPGD (0.34) | ALDH1A1F2GLAHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11020488-B2 | Pyrroloquinolin compounds and methods of using same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200129631-A1 | PYRROLOQUINOLIN COMPOUNDS AND METHODS OF USING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11020488-B2 | Pyrroloquinolin compounds and methods of using same | POLQ, SYNCRIP, PCNA | ALDH1A1 1739/4885F2 2023/4885GLA 3607/4885 |
| US-20200129631-A1 | PYRROLOQUINOLIN COMPOUNDS AND METHODS OF USING SAME | POLQ, SYNCRIP, PCNA | ALDH1A1 1739/4885F2 2023/4885GLA 3607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.