Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108040 | 0.85 | HTT (0.60) | HTTALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL11100872 | 0.79 | MYC (0.52) | ALDH1A1SMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL1591440 | 0.78 | ALDH1A1 (0.62) | HTTALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL6894325 | 0.77 | ALDH1A1 (0.71) | HTTALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL1672017 | 0.75 | HTT (1.00) | HTTALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL11105710 | 0.75 | HTT (0.73) | HTTALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL11161561 | 0.75 | HTT (0.73) | HTTALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL1672019 | 0.75 | HTT (0.65) | HTTALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL1811947 | 0.75 | SMN1; SMN2 (0.76) | HTTALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL1671812 | 0.74 | HTT (0.79) | HTTALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063826-B1 | 2-AMINO-BENZOIC-ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES OR INTERMEDIATES | Dr. Karl Thomae GmbH (DE) | 1984-12-05 | — | — | EP | disclosed |
| EP-0063826-A2 | 2-Amino-benzoic-acid derivatives, their preparation and their use as medicines or intermediates | Dr. Karl Thomae GmbH (DE) | 1982-11-03 | — | — | EP | disclosed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |