SCHEMBL11097085

SCHEMBL11097085

COc1ccc(OC(=O)CS)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.60
HDAC4 P56524 1/20 0.60
HDAC1 Q13547 1/20 0.60
HDAC7 Q8WUI4 1/20 0.60
HDAC2 Q92769 1/20 0.60
HDAC10 Q969S8 1/20 0.60
HDAC11 Q96DB2 1/20 0.60
HDAC8 Q9BY41 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
HDAC9 Q9UKV0 1/20 0.60
HDAC5 Q9UQL6 1/20 0.60
LMNA P02545 3/20 0.56
GAA P10253 3/20 0.56
KMT2A Q03164 3/20 0.53
HSD17B10 Q99714 2/20 0.53
ALDH1A1 P00352 1/20 0.53
MAPT P10636 1/20 0.53
HTT P42858 1/20 0.53
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL198474 0.83 LMNA (0.57) LMNAGAAKMT2AHSD17B10ALDH1A1
SCHEMBL5130508 0.83 HTT (0.63) LMNAGAAKMT2AHSD17B10ALDH1A1
SCHEMBL8631220 0.83 KMT2A (0.76) LMNAGAAKMT2AHSD17B10ALDH1A1
SCHEMBL23818361 0.83 KMT2A (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL819434 0.81 KMT2A (0.66) LMNAGAAKMT2AHSD17B10ALDH1A1
SCHEMBL4643749 0.81 LMNA (0.58) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL4645765 0.79 GAA (0.56) LMNAGAAKMT2AHSD17B10ALDH1A1
SCHEMBL3360371 0.79 KMT2A (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL14620779 0.79 GAA (0.56) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8483877 0.79 KMT2A (0.47) LMNAKMT2AHSD17B10ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102193315-B Colouring photosensitive resin composition SUMITOMO CHEMICAL CO 2015-01-14 CN disclosed
CN-103376654-A Color photosensitive resin composition SUMITOMO CHEMICAL CO 2013-10-30 CN disclosed
CN-102193315-A Colouring photosensitive resin composition SUMITOMO CHEMICAL CO 2011-09-21 CN disclosed
US-4461911-A FROM THIOGLYCOLIC ACID AND AN ARYLDIAZONIUM SALT, COPPER SALT, ACID MEDIUM BAYER AKTIENGESELLSCHAFT (DE) 1984-07-24 US disclosed