Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095285 | 0.89 | KMT2A (0.52) | GAALMNAALDH1A1HTTKMT2A | |
| SCHEMBL11745384 | 0.85 | AKR1C3 (0.51) | LMNAALDH1A1KMT2AMAPTHSD17B10 | |
| SCHEMBL4642418 | 0.84 | KMT2A (0.60) | GAALMNAALDH1A1HTTKMT2A | |
| SCHEMBL10500407 | 0.83 | LMNA (0.57) | GAALMNAALDH1A1HTTKMT2A | |
| SCHEMBL5130508 | 0.83 | HTT (0.63) | GAALMNAALDH1A1HTTKMT2A | |
| SCHEMBL8631220 | 0.83 | KMT2A (0.76) | GAALMNAALDH1A1HTTKMT2A | |
| SCHEMBL4644919 | 0.81 | KMT2A (0.56) | GAALMNAALDH1A1HTTKMT2A | |
| SCHEMBL4643847 | 0.81 | CA1 (0.58) | LMNAALDH1A1HTTKMT2AMAPT | |
| SCHEMBL4643749 | 0.81 | LMNA (0.58) | GAALMNAALDH1A1HTTKMT2A | |
| SCHEMBL819434 | 0.81 | KMT2A (0.66) | GAALMNAALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63002986-A | — | — | None | — | — | JP | disclosed |
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| EP-1487928-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | Jotun AS (NO) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080747-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2003-10-02 | — | — | WO | disclosed |
| EP-0251141-B1 | PIPERAZINE COMPOUNDS, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | KANEBO, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4797400-A | 1-4METHOXYPHENOXYCARBONYLMETHYL-4-(3,4,5-TRIMETHOXYBENZYLPIPERAZINE | KANEBO, LTD. (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0251141-A1 | Piperazine compounds, process for preparing them, pharmaceutical composition and use | KANEBO, LTD. (JP) | 1988-01-07 | — | — | EP | disclosed |
| JP-S632986-A | NOVEL PIPERAZINE DERIVATIVE AND ANTIULCER AGENT CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD | 1988-01-07 | — | — | JP | disclosed |