Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | GLA | P06280 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29532206 | 0.85 | KDM4E (1.00) | GAAKDM4EHPGDALDH1A1GLA | |
| SCHEMBL592109 | 0.85 | KDM4E (1.00) | GAAKDM4EHPGDALDH1A1GLA | |
| SCHEMBL31475465 | 0.80 | LMNA (0.67) | GAAKDM4EHPGDALDH1A1GLA | |
| SCHEMBL9724162 | 0.80 | LMNA (0.67) | GAAKDM4EHPGDALDH1A1GLA | |
| SCHEMBL3151814 | 0.77 | LMNA (1.00) | GAAKDM4EHPGDALDH1A1GLA | |
| SCHEMBL1224662 | 0.77 | LMNA (0.62) | GAAKDM4EHPGDALDH1A1GLA | |
| SCHEMBL1420703 | 0.77 | LMNA (0.62) | GAAKDM4EHPGDALDH1A1GLA | |
| SCHEMBL11468572 | 0.77 | LMNA (0.62) | GAAKDM4EHPGDALDH1A1GLA | |
| SCHEMBL4482742 | 0.77 | LMNA (0.62) | GAAKDM4EHPGDALDH1A1GLA | |
| SCHEMBL28982768 | 0.77 | KDM4E (0.63) | GAAKDM4EHPGDALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1271056-C | Quinolinone compounds and preparing process and intermediate thereof | UNIV ZHEJIANG TECHNOLOGY (CN) | 2006-08-23 | — | — | CN | claimed |
| CN-1594295-A | Quinolinone compounds and preparing process and intermediate thereof | UNIV ZHEJIANG TECHNOLOGY (CN) | 2005-03-16 | — | — | CN | claimed |
| CN-118272274-B | Lactic acid bacteria starter and application thereof in preparation of blueberry corn peptide fermentation liquor | 齐齐哈尔大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-118272274-A | Lactic acid bacteria starter and application thereof in preparation of blueberry corn peptide fermentation liquor | 齐齐哈尔大学 | 2024-07-02 | — | — | CN | disclosed |
| WO-2017072796-A1 | 2-PYRIDONE BASED COMPOUNDS USEFUL AS POTENTIAL PHOSPHODIESTERASE3A (PDE3A)INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-04 | — | — | WO | disclosed |
| CN-1271056-C | Quinolinone compounds and preparing process and intermediate thereof | UNIV ZHEJIANG TECHNOLOGY (CN) | 2006-08-23 | — | — | CN | disclosed |
| CN-1594295-A | Quinolinone compounds and preparing process and intermediate thereof | UNIV ZHEJIANG TECHNOLOGY (CN) | 2005-03-16 | — | — | CN | disclosed |
| US-4427680-A | ANTHISTAMINES | BOEHRINGER MANNHEIM GMBH (DE) | 1984-01-24 | — | — | US | disclosed |
| EP-0003771-B1 | CARBOSTYRILE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1982-10-20 | — | — | EP | disclosed |
| US-4330549-A | Coumarins connected via an oxyalkyl group with a piperidine ring having anti-allergic action | BOEHRINGER MANNHEIM GMBH (DE) | 1982-05-18 | — | — | US | disclosed |
| US-4329347-A | Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril | BOEHRINGER INGELHEIM GMBH (DE) | 1982-05-11 | — | — | US | disclosed |
| EP-0013894-B1 | ARYLETHERS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1982-02-03 | — | — | EP | disclosed |
| EP-0006506-B1 | CARBOSTYRILE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1981-09-16 | — | — | EP | disclosed |
| US-4234585-A | ANTIALLERGENS, HYPOTENSIVE | BOEHRINGER MANNHEIM GMBH (DE) | 1980-11-18 | — | — | US | disclosed |
| EP-0013894-A1 | Arylethers, process for their preparation and medicines containing them | Roche Diagnostics GmbH (DE) | 1980-08-06 | — | — | EP | disclosed |
| EP-0006506-A1 | Carbostyrile derivatives, processes for their preparation and pharmaceutical compositions containing them | Roche Diagnostics GmbH (DE) | 1980-01-09 | — | — | EP | disclosed |
| EP-0003771-A1 | Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | disclosed |