Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 5/20 | 1.00 |
| ▸ | GLA | P06280 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | TNKS2 | Q9H2K2 | 9/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GLI1 | P08151 | 1/20 | 0.47 |
| ▸ | GLI2 | P10070 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL592109 | 1.00 | KDM4E (1.00) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL14978967 | 0.87 | KDM4E (0.77) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL11097088 | 0.85 | GAA (0.73) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL22461494 | 0.82 | KDM4E (0.69) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL12668286 | 0.80 | ALDH1A1 (0.67) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL2795205 | 0.80 | KDM4E (0.67) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL8581212 | 0.79 | KDM4E (0.66) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL8064223 | 0.77 | KDM4E (0.62) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL13264599 | 0.77 | KDM4E (0.62) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL2798886 | 0.77 | KDM4E (0.62) | KDM4EGAAGLAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997462-A1 | ASSAYS FOR IMPROVING AUTOMATED ANTIMICROBIAL SUSCEPTIBILITY TESTING ACCURACY | Selux Diagnostics Inc. (US) | 2022-05-18 | — | — | EP | disclosed |