Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10787743 | 0.78 | TSHR (0.42) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL149491 | 0.78 | TSHR (0.42) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL10998222 | 0.78 | TSHR (0.42) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL28548128 | 0.76 | NPSR1 (0.37) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL49520 | 0.74 | TSHR (0.48) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL9181403 | 0.74 | TSHR (0.48) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL717181 | 0.74 | TSHR (0.48) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL980166 | 0.71 | TSHR (0.40) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL233879 | 0.71 | TSHR (0.40) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL28846577 | 0.71 | KMT2A (0.36) | TSHRALDH1A1NPSR1ALOX12L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112434-A2 | Hydrogen bearing silyl carbamates | UNION CARBIDE CORPORATION (US) | 1984-07-04 | — | — | EP | disclosed |
| US-4400526-A | Hydrogen bearing silyl carbamates | UNION CARBIDE CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |