Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095593 | 0.72 | CA2 (1.00) | CA2POLBALDH1A1GAAUSP2 | |
| SCHEMBL10567559 | 0.72 | KDM4E (0.54) | ALDH1A1GAAMPIAPOBEC3GKMT2A | |
| SCHEMBL7378242 | 0.71 | CA2 (0.61) | CA2POLBALDH1A1GAAMPI | |
| SCHEMBL11448749 | 0.69 | CA2 (0.50) | CA2POLBALDH1A1GAAMPI | |
| SCHEMBL9660225 | 0.69 | MEN1 (0.69) | CA2POLBALDH1A1GAAMPI | |
| SCHEMBL8941120 | 0.69 | CA2 (0.53) | CA2 | |
| SCHEMBL28164756 | 0.69 | CA2 (0.91) | CA2POLBALDH1A1GAAUSP2 | |
| SCHEMBL29449205 | 0.69 | CA2 (0.91) | CA2POLBALDH1A1GAAUSP2 | |
| SCHEMBL30018700 | 0.67 | SIRT2 (0.75) | CA2ALDH1A1DAOCYP3A4KMT2A | |
| SCHEMBL1486318 | 0.65 | CA2 (0.68) | CA2POLBALDH1A1GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123402-A2 | Pyrimidine derivatives, preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |