Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448749 | 0.86 | CA2 (0.50) | CA2 | |
| SCHEMBL10849271 | 0.83 | — | — | |
| SCHEMBL10850053 | 0.81 | — | — | |
| SCHEMBL9090379 | 0.79 | DPYD (0.70) | — | |
| SCHEMBL7714193 | 0.75 | — | — | |
| SCHEMBL1059989 | 0.74 | PNP (0.67) | — | |
| SCHEMBL30593602 | 0.72 | — | — | |
| SCHEMBL18796800 | 0.72 | PDE3B (0.68) | CA2 | |
| SCHEMBL11448328 | 0.72 | DHFR (0.50) | CA2 | |
| SCHEMBL5800398 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491234-A | Pyrimidine derivatives for enhancing antitumor activity | PFIZER INC. (US) | 1996-02-13 | — | — | US | disclosed |
| EP-0580753-B1 | PYRIMIDINE DERIVATIVES FOR ENHANCING ANTITUMOR ACTIVITY | PFIZER (US) | 1995-03-01 | — | — | EP | disclosed |