Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097303 | 0.90 | EPHX2 (0.42) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11096193 | 0.89 | CYP1A2 (0.42) | MAPTSMN1; SMN2LMNACYP1A2TP53 | |
| SCHEMBL11095436 | 0.88 | TDP1 (0.41) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11098428 | 0.88 | MAPT (0.55) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11270736 | 0.82 | MAPT (0.49) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11300326 | 0.81 | MAPT (0.42) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10915313 | 0.81 | MAPT (0.47) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11182317 | 0.81 | MAPT (0.55) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11123131 | 0.80 | MAPT (0.43) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10684245 | 0.80 | MAPT (0.47) | MAPTKMT2AMEN1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024931-B1 | 1,2,4-BENZOTRIAZINYLAMINOPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1984-10-17 | — | — | EP | claimed |
| EP-0024931-B1 | 1,2,4-BENZOTRIAZINYLAMINOPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1984-10-17 | — | — | EP | disclosed |
| US-4310347-A | Herbicidal 1,2,4-benzotriazines | ICI AUSTRALIA LIMITED (AU) | 1982-01-12 | — | — | US | disclosed |
| EP-0024931-A2 | 1,2,4-Benzotriazinylaminophenoxyalkane carboxylic acid derivatives, processes for their preparation and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-03-11 | — | — | EP | disclosed |