Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097303 | 0.92 | EPHX2 (0.42) | TDP1GAAL3MBTL1CYP1A2MAPT | |
| SCHEMBL11097512 | 0.88 | MAPT (0.46) | L3MBTL1CYP1A2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11096193 | 0.86 | CYP1A2 (0.42) | TDP1GAACYP1A2MAPTALDH1A1 | |
| SCHEMBL11098428 | 0.84 | MAPT (0.55) | L3MBTL1CYP1A2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11267012 | 0.84 | MAPT (0.46) | TDP1GAAL3MBTL1CYP1A2MAPT | |
| SCHEMBL11129847 | 0.83 | TDP1 (0.38) | TDP1GAAL3MBTL1CYP1A2MAPT | |
| SCHEMBL11124251 | 0.82 | PPARA (0.46) | — | |
| SCHEMBL11131778 | 0.81 | CYP1A2 (0.38) | TDP1GAAL3MBTL1CYP1A2MAPT | |
| SCHEMBL11097255 | 0.80 | KMT2A (0.39) | TDP1GAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL10730420 | 0.78 | L3MBTL1 (0.42) | TDP1GAAL3MBTL1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024931-B1 | 1,2,4-BENZOTRIAZINYLAMINOPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1984-10-17 | — | — | EP | claimed |
| EP-0024931-B1 | 1,2,4-BENZOTRIAZINYLAMINOPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1984-10-17 | — | — | EP | disclosed |
| US-4310347-A | Herbicidal 1,2,4-benzotriazines | ICI AUSTRALIA LIMITED (AU) | 1982-01-12 | — | — | US | disclosed |
| EP-0024931-A2 | 1,2,4-Benzotriazinylaminophenoxyalkane carboxylic acid derivatives, processes for their preparation and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-03-11 | — | — | EP | disclosed |