SCHEMBL11097616

SCHEMBL11097616

CCN1CNC(=O)NC1=N

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.31
CRBN Q96SW2 1/20 0.31
INMT O95050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11101804 0.85 KMT2A (0.33) KMT2A
SCHEMBL11097087 0.81 CRBN (0.34) KMT2ACRBN
SCHEMBL11097530 0.79 KMT2A (0.32) KMT2A
SCHEMBL11099807 0.79
SCHEMBL11099671 0.76 TAAR1 (0.33) KMT2ACRBN
SCHEMBL11104026 0.72
SCHEMBL12293892 0.71
SCHEMBL11097010 0.69 KMT2A (0.36) KMT2A
SCHEMBL11098814 0.68 GRM5 (0.32) KMT2A
SCHEMBL11100171 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4477442-A PENTOFURANOSYL-5,6-DIHYDROTRIAZINES IN TREATMENT OF VIRAL DISEASES THE UPJOHN COMPANY (US) 1984-10-16 US disclosed
US-4423212-A Nucleosides and process THE UPJOHN COMPANY (US) 1983-12-27 US disclosed
US-4239753-A Composition of matter and process THE UPJOHN COMPANY (US) 1980-12-16 US disclosed
US-4171431-A Nucleosides and process THE UPJOHN COMPANY (US) 1979-10-16 US disclosed