SCHEMBL11099671

SCHEMBL11099671

CCN1CNC(=O)NC1=S

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.33
ALDH1A1 P00352 2/20 0.32
THRB P10828 1/20 0.32
CNR1 P21554 1/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11104438 0.85 KMT2A (0.38) TAAR1ALDH1A1THRBCNR1KMT2A
SCHEMBL11097087 0.81 CRBN (0.34) KMT2ACRBN
SCHEMBL11099538 0.79
SCHEMBL11107959 0.79 KMT2A (0.32) KMT2A
SCHEMBL11097616 0.76 KMT2A (0.31) KMT2ACRBN
SCHEMBL11100470 0.73 ALDH1A1 (0.33) TAAR1ALDH1A1
SCHEMBL11102459 0.72
SCHEMBL10653236 0.71
SCHEMBL12293892 0.71
SCHEMBL11097010 0.69 KMT2A (0.36) TAAR1THRBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4477442-A PENTOFURANOSYL-5,6-DIHYDROTRIAZINES IN TREATMENT OF VIRAL DISEASES THE UPJOHN COMPANY (US) 1984-10-16 US disclosed
US-4423212-A Nucleosides and process THE UPJOHN COMPANY (US) 1983-12-27 US disclosed
US-4239753-A Composition of matter and process THE UPJOHN COMPANY (US) 1980-12-16 US disclosed
US-4171431-A Nucleosides and process THE UPJOHN COMPANY (US) 1979-10-16 US disclosed