Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492049 | 0.90 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL9492917 | 0.84 | NPC1 (0.30) | NPC1RAB9A | |
| SCHEMBL10881231 | 0.83 | LMNA (0.39) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL10899040 | 0.80 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL10880745 | 0.77 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1NPC1KDM4EMEN1 | |
| SCHEMBL10880739 | 0.77 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1NPC1KDM4EMEN1 | |
| SCHEMBL11202912 | 0.76 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL10899048 | 0.76 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL9493987 | 0.75 | — | — | |
| SCHEMBL9492279 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489069-A | ANTITUMOR | CIBA-GEIGY AG (CH) | 1984-12-18 | — | — | US | claimed |
| US-4489069-A | ANTITUMOR | CIBA-GEIGY AG (CH) | 1984-12-18 | — | — | US | disclosed |
| EP-0085275-A1 | Substituted thiazolidinylic esters of mineral acids | CIBA-GEIGY AG (CH) | 1983-08-10 | — | — | EP | disclosed |