Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471316 | 0.85 | HPGD (0.63) | HPGDALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL5471315 | 0.85 | HPGD (0.63) | HPGDALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL11096886 | 0.80 | HPGD (0.56) | HPGDALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL5482495 | 0.78 | HDAC1 (0.56) | HPGDALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL5475097 | 0.78 | HDAC1 (0.56) | HPGDALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL4886558 | 0.78 | LMNA (0.57) | HPGDALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL11438845 | 0.78 | HPGD (0.57) | HPGDALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL5482492 | 0.78 | HPGD (0.57) | HPGDALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL13531660 | 0.78 | HPGD (0.57) | HPGDALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL5475095 | 0.78 | HPGD (0.57) | HPGDALDH1A1HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481203-A | ANTICANCER AGENTS | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1984-11-06 | — | — | US | disclosed |