SCHEMBL4886558

SCHEMBL4886558

O=c1c(F)cn(C2CCCO2)c(=O)n1C1CCCO1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.57
HPGD P15428 1/20 0.57
ESR1 P03372 1/20 0.57
MAPT P10636 1/20 0.57
ALDH1A1 P00352 6/20 0.55
HDAC1 Q13547 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
KMT2A Q03164 4/20 0.43
POLB P06746 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSP90AA1 P07900 7/20 0.41
MEN1 O00255 3/20 0.38
TP53 P04637 1/20 0.33
CYP2C9 P11712 1/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
APEX1 P27695 1/20 0.33
PI4KA P42356 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11096840 0.95 HPGD (0.53) LMNAHPGDESR1MAPTALDH1A1
SCHEMBL11436751 0.84 HPGD (0.52) LMNAHPGDESR1MAPTALDH1A1
SCHEMBL11096886 0.84 HPGD (0.56) LMNAHPGDESR1MAPTALDH1A1
SCHEMBL27244485 0.84 ALDH1A1 (0.57) LMNAHPGDESR1MAPTALDH1A1
SCHEMBL9097192 0.82 LMNA (0.55) LMNAHPGDESR1MAPTALDH1A1
SCHEMBL9839604 0.82 ALDH1A1 (0.43) LMNAHPGDESR1MAPTALDH1A1
SCHEMBL5471316 0.81 HPGD (0.63) LMNAHPGDESR1MAPTALDH1A1
SCHEMBL5471315 0.81 HPGD (0.63) LMNAHPGDESR1MAPTALDH1A1
SCHEMBL11236896 0.78 HDAC1 (0.42) LMNAHPGDESR1MAPTALDH1A1
SCHEMBL11098296 0.78 HPGD (0.60) LMNAHPGDESR1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724477-A1 CIRCULARIZED ANTIBODY MOLECULES Regeneron Pharmaceuticals, Inc. (US) 2026-04-15 EP claimed
US-20260004482-A1 METHOD, SYSTEM, AND DEVICE FOR ULTRA-LOW-DOSE ORAL CBCT IMAGING CHINA-JAPAN FRIENDSHIP HOSPITAL (CHINA JAPAN FRIENDSHIP CLINICAL MEDICAL RESEARCH INSTITUTE) (CN) 2026-01-01 US claimed
EP-4213135-B1 SECURE EXPONENT UNIFICATION SYSTEM, SECURE EXPONENT UNIFICATION APPARATUS, SECURE EXPONENT UNIFICATION METHOD, SECURE SUM COMPUTING SYSTEM, SECURE SUM-OF-PRODUCT COMPUTING SYSTEM, AND PROGRAM NTT INC (JP) 2025-12-24 EP claimed
EP-4634019-A1 SYSTEM FOR CONTROLLING BRAKING/TRACTION OF AN ELECTRIC OR HYBRID VEHICLE Brembo S.p.A. (IT) 2025-10-22 EP claimed
EP-4210028-B1 SECURE SHIFT SYSTEM, SECURE SHIFT APPARATUS, SECURE SHIFT METHOD, AND PROGRAM NIPPON TELEGRAPH & TELEPHONE (JP) 2025-06-11 EP claimed
CN-119954766-A Rosin alkane type diterpenoid compound and extraction method and application thereof 河北医科大学 2025-05-09 CN claimed
WO-2025092272-A1 METHOD, SYSTEM AND APPARATUS FOR ORAL CAVITY CBCT ULTRALOW-DOSE IMAGING 中日友好医院(中日友好临床医学研究所) 2025-05-08 WO claimed
CN-119696961-A Channel estimation method, terminal and medium based on meta-learning under ultra-large-scale MIMO 重庆邮电大学 2025-03-25 CN claimed
CN-116324934-B Secret shift system, secret shift device, secret shift method, and recording medium 日本电信电话株式会社 2025-02-25 CN claimed
US-20250011449-A1 CIRCULARIZED ANTIBODY MOLECULES REGENERON PHARMACEUTICALS, INC. (US) 2025-01-09 US claimed
WO-2022079890-A1 SECRET SHIFT SYSTEM, SECRET SHIFT DEVICE, SECRET SHIFT METHOD, AND PROGRAM 日本電信電話株式会社 2022-04-21 WO claimed
EP-3984543-A1 USE OF EXTRACT FROM RABBIT SKIN INFLAMED BY VACCINIA VIRUS IN TREATMENT OF CANCER Mega Winning Limited (HK) 2022-04-20 EP claimed
CN-114236374-A Real-time diagnosis method for open circuit fault of rectifier 中国矿业大学 2022-03-25 CN claimed
WO-2022060993-A1 SYSTEM AND METHOD FOR INTEGRATED BLOOD VESSEL EMBOLIZATION AND LOCALIZED DRUG DELIVERY FARHA SAID (US) 2022-03-24 WO claimed
CN-114138543-A Data strip coding method, system, device and medium 深信服科技股份有限公司 2022-03-04 CN claimed
EP-3951419-A1 APPARATUS COMPRISING AT LEAST ONE PROCESSOR Nokia Technologies Oy (FI) 2022-02-09 EP claimed
US-4914105-A NONTOXIC, REDUCED SIDE EFFECTS FUJII SETSURO (JP) 1990-04-03 US claimed
US-4719213-A Anti-cancer composition for delivering 5-fluorouracil TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1988-01-12 US claimed
US-4371535-A Method of and composition for delivering 5-fluorouracil to tumors TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1983-02-01 US claimed
US-4249006-A Method of producing 5-fluorouracil derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-02-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260004482-A1 METHOD, SYSTEM, AND DEVICE FOR ULTRA-LOW-DOSE ORAL CBCT IMAGING BECN1, NCDN, OGT LMNA 3402/4885HPGD 3638/4885ESR1 1503/4885
US-20250011449-A1 CIRCULARIZED ANTIBODY MOLECULES IGLV6-57, IGSF11, CD2BP2 LMNA 4176/4885HPGD 4489/4885ESR1 4056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.