Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | TTR | P02766 | 1/20 | 0.69 |
| ▸ | ALB | P02768 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18153628 | 0.86 | MEN1 (0.57) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL11100611 | 0.85 | HSPB1 (0.56) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL11103098 | 0.85 | MEN1 (0.58) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL10884753 | 0.83 | TDP1 (0.55) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL24635453 | 0.82 | TDP1 (0.65) | MEN1KMT2ATDP1TTRALB | |
| Aclonifen SCHEMBL55487 | 0.82 | MEN1 (1.00) | MEN1KMT2ATDP1TTRALB | |
| Aclonifen SCHEMBL4894870 | 0.82 | MEN1 (1.00) | MEN1KMT2ATDP1TTRALB | |
| Aclonifen SCHEMBL29470834 | 0.82 | MEN1 (1.00) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL938815 | 0.82 | MEN1 (0.69) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL21295387 | 0.81 | TDP1 (0.52) | MEN1KMT2ATDP1TTRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061110-B1 | NITRO-ANILINES | CELAMERCK GmbH & Co. KG (DE) | 1984-08-08 | — | — | EP | disclosed |
| EP-0061110-A1 | Nitro-anilines | CELAMERCK GmbH & Co. KG (DE) | 1982-09-29 | — | — | EP | disclosed |