Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.46 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024545 | 0.85 | LMNA (0.61) | LMNAASAH1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL23322830 | 0.81 | LMNA (0.46) | LMNAASAH1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL10656213 | 0.79 | SMN1; SMN2 (0.57) | LMNAASAH1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL17897700 | 0.79 | LMNA (0.54) | LMNASMN1; SMN2KDM4ECYP1A2GRIA1 | |
| SCHEMBL11040533 | 0.78 | LMNA (0.44) | LMNAASAH1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL11159032 | 0.78 | LMNA (0.44) | LMNAASAH1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL10656853 | 0.77 | LMNA (0.49) | LMNAASAH1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL3823927 | 0.77 | SMN1; SMN2 (0.62) | LMNAASAH1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL25965763 | 0.76 | LMNA (0.42) | LMNAASAH1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL15616807 | 0.75 | LMNA (0.46) | LMNAASAH1SMN1; SMN2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481203-A | ANTICANCER AGENTS | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1984-11-06 | — | — | US | disclosed |