Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098481 | 1.00 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2POLBKDM4E | |
| SCHEMBL29422996 | 1.00 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2POLBKDM4E | |
| SCHEMBL11814277 | 0.75 | ALDH1A1 (0.69) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL18209594 | 0.73 | CHRM2 (0.44) | ALDH1A1LMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL16206523 | 0.73 | CHRM2 (0.44) | ALDH1A1LMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL8434500 | 0.70 | CHRNB2 (0.42) | — | |
| SCHEMBL11813845 | 0.70 | ALDH1A1 (0.62) | ALDH1A1CYP3A4TSHRTHPOMAPK1 | |
| SCHEMBL2486876 | 0.70 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL10077960 | 0.69 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL22771080 | 0.69 | HCAR2 (0.39) | ALDH1A1LMNAPOLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569629-B1 | DETECTION OF NICOTINE METABOLITES | GFC DIAGNOSTICS LTD (GB) | 2015-08-19 | — | — | EP | disclosed |
| US-4442292-A | LARVICIDES | PHILIP MORRIS INCORPORATED (US) | 1984-04-10 | — | — | US | disclosed |