Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864904 | 0.86 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL6971889 | 0.83 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL161 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL13199726 | 0.82 | AGTR2 (0.59) | AGTR1AGTR2 | |
| SCHEMBL11100430 | 0.81 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9424075 | 0.72 | — | — | |
| SCHEMBL9424073 | 0.72 | — | — | |
| SCHEMBL1986629 | 0.71 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL9473439 | 0.71 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9194373 | 0.71 | AGTR1 (1.00) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028833-B1 | IMIDAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-01-25 | — | — | EP | disclosed |
| US-4340598-A | Hypotensive imidazole derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-07-20 | — | — | US | disclosed |
| EP-0028833-A2 | Imidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-05-20 | — | — | EP | disclosed |