Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6054462 | 0.86 | NISCH (0.69) | NISCHADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11097073 | 0.81 | NISCH (0.67) | NISCHADRA2AADRA2BADRA2CLMNA | |
| Isaglidole SCHEMBL114184 | 0.79 | NISCH (0.72) | NISCHADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL8091334 | 0.79 | NISCH (1.00) | NISCHADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL11001474 | 0.79 | NISCH (0.72) | NISCHADRA2AADRA2BADRA2CADRA1D | |
| Isaglidole SCHEMBL30659750 | 0.79 | NISCH (0.72) | NISCHADRA2AADRA2BADRA2CLMNA | |
| Hydrochloric Acid SCHEMBL6513698 | 0.78 | NISCH (0.97) | NISCHADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL9619232 | 0.77 | NISCH (0.58) | NISCHADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11130285 | 0.75 | NISCH (0.59) | NISCHADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL11418650 | 0.74 | NISCH (0.55) | NISCHADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062844-B1 | SUBSTITUTED BENZO(DE)ISOQUINOLINES, PROCESSES FOR THEIR PREPARATION, AND THEIR APPLICATION AS PHARMACEUTICAL PREPARATIONS | Beiersdorf Aktiengesellschaft (DE) | 1984-11-28 | — | — | EP | claimed |