Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | ATP4A | P20648 | 1/20 | 0.45 |
| ▸ | ATP4B | P51164 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100065 | 0.87 | ATP4A (0.47) | MAOBATP4AATP4BPPARG | |
| SCHEMBL11098840 | 0.85 | DRD4 (0.44) | MAOBMAOAALDH1A1GAAL3MBTL1 | |
| SCHEMBL11096460 | 0.84 | DRD4 (0.43) | MAOBMAOAFFAR4ALDH1A1GAA | |
| SCHEMBL11099677 | 0.83 | KDM4E (0.47) | MAOBMAOAFFAR4KDM4EALDH1A1 | |
| SCHEMBL9746834 | 0.82 | PPARG (0.50) | MAOBMAOAATP4AATP4BKDM4E | |
| SCHEMBL11093758 | 0.82 | MAOB (0.43) | MAOBMAOAATP4AATP4BALDH1A1 | |
| SCHEMBL2189993 | 0.81 | ATP4A (0.60) | ATP4AATP4BKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL11707204 | 0.81 | MAOB (0.52) | MAOBMAOAATP4AATP4BFFAR4 | |
| SCHEMBL2191140 | 0.79 | MEN1 (0.51) | ATP4AATP4BKDM4EALDH1A1PPARG | |
| SCHEMBL2191240 | 0.78 | PPARG (0.67) | ATP4AATP4BALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033094-B1 | IMIDAZO(1,2-A)PYRIDINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1984-10-10 | — | — | EP | disclosed |
| EP-0033094-A1 | Imidazo(1,2-a)pyridines, processes for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1981-08-05 | — | — | EP | disclosed |