Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.60 |
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22361969 | 0.81 | TDP1 (0.60) | MAPTNPSR1TDP1MAPK1KDM4E | |
| SCHEMBL22361970 | 0.81 | TDP1 (0.60) | MAPTNPSR1TDP1MAPK1KDM4E | |
| SCHEMBL6204204 | 0.81 | TDP1 (0.56) | MAPTNPSR1TDP1MAPK1KDM4E | |
| SCHEMBL8345057 | 0.76 | TRPA1 (0.43) | TDP1KDM4EMPOALOX15TSHR | |
| SCHEMBL3128715 | 0.75 | MPO (0.42) | MAPTMAPK1KDM4EMPOTSHR | |
| SCHEMBL11177994 | 0.74 | MAPT (0.45) | MAPTNPSR1TDP1MAPK1KDM4E | |
| SCHEMBL11097542 | 0.71 | MAPT (0.55) | MAPTNPSR1TDP1MAPK1KDM4E | |
| SCHEMBL28544062 | 0.71 | MPO (0.44) | MAPTNPSR1TDP1MAPK1KDM4E | |
| SCHEMBL4366664 | 0.71 | MPO (0.44) | MAPTNPSR1TDP1MAPK1KDM4E | |
| SCHEMBL30605805 | 0.70 | MAPT (0.91) | MAPTNPSR1TDP1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061082-B1 | PROCESS FOR THE PREPARATION OF 2,3-DIHYDRO-4H-1,4-BENZOTHIAZINES | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| US-4393206-A | DEHYDROCYCLIZATION OF 2-(2-HYDROXYALKYL)-THIOANILINES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| EP-0061082-A1 | Process for the preparation of 2,3-dihydro-4H-1,4-benzothiazines | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |