Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819044 | 0.86 | PROKR1 (0.47) | PROKR1 | |
| SCHEMBL11340185 | 0.85 | KDM4E (0.55) | PROKR1 | |
| SCHEMBL27992641 | 0.84 | KDM4E (0.38) | PROKR1 | |
| SCHEMBL4306410 | 0.83 | PROKR1 (0.45) | PROKR1 | |
| Hydrochloric Acid SCHEMBL15973575 | 0.83 | KDM4E (0.53) | PROKR1 | |
| SCHEMBL14534850 | 0.80 | CRHR1 (0.43) | PROKR1 | |
| SCHEMBL26555466 | 0.80 | PLK1 (0.46) | PROKR1 | |
| SCHEMBL31627489 | 0.79 | PROKR1 (0.43) | PROKR1 | |
| SCHEMBL27584824 | 0.79 | GABRP (0.40) | PROKR1 | |
| SCHEMBL11346493 | 0.79 | KDM4E (0.50) | PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051371-B1 | IMIDAZOLYLPYRIDINE THERAPEUTIC AGENTS | PFIZER INC. (US) | 1984-08-29 | — | — | EP | disclosed |
| EP-0051371-A2 | Imidazolylpyridine therapeutic agents | PFIZER INC. (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4302464-A | ANTIULCER AGENTS, ANTI-H2-HISTAMINES | PFIZER INC. (US) | 1981-11-24 | — | — | US | disclosed |