Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18897096 | 0.82 | THRB (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL4827346 | 0.79 | TSHR (0.38) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL18469709 | 0.78 | TSHR (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Chloromethane SCHEMBL252738 | 0.78 | TSHR (0.36) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL4568747 | 0.76 | TSHR (0.37) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Hydrochloric Acid SCHEMBL327649 | 0.76 | TSHR (0.35) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL24690682 | 0.76 | TSHR (0.47) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ethylamine SCHEMBL27453778 | 0.75 | TSHR (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Acrylamide SCHEMBL3885951 | 0.74 | TSHR (0.42) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1602185 | 0.74 | TSHR (0.35) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126866-A1 | Organic amine salt of an acid, manufacture and use as accelerator | DENTSPLY INTERNATIONAL, INC. (US) | 1984-12-05 | — | — | EP | disclosed |