Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098562 | 0.91 | OPRM1 (0.60) | OPRM1 | |
| SCHEMBL11027089 | 0.91 | CHRM1 (0.55) | OPRM1 | |
| SCHEMBL11097925 | 0.90 | OPRM1 (0.52) | OPRM1 | |
| SCHEMBL11024054 | 0.90 | DRD2 (0.55) | OPRM1 | |
| SCHEMBL11029089 | 0.90 | OPRM1 (0.58) | OPRM1 | |
| SCHEMBL11096216 | 0.89 | OPRM1 (0.57) | OPRM1 | |
| SCHEMBL11024019 | 0.89 | OPRM1 (0.54) | OPRM1 | |
| SCHEMBL11024114 | 0.87 | OPRM1 (0.54) | OPRM1 | |
| SCHEMBL11024057 | 0.87 | DRD2 (0.55) | OPRM1 | |
| SCHEMBL11022277 | 0.87 | CHRM1 (0.54) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4470989-A | Neuroleptic n-oxacyclyl-alkylpiperidine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |
| EP-0068261-A1 | N-oxacyclyl-alkylpiperidine derivatives, their preparation, pharmaceutical preparations containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |