Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096759 | 0.86 | TACR3 (0.39) | TACR3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11079267 | 0.77 | KMT2A (0.40) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11099466 | 0.77 | MEN1 (0.39) | TACR3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11099295 | 0.76 | TOP2A (0.43) | KDM4EMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL11088487 | 0.76 | MEN1 (0.51) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11099232 | 0.75 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL11088483 | 0.74 | KMT2A (0.42) | TACR3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10370567 | 0.74 | KDM4E (0.44) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11090325 | 0.73 | KDM4E (0.48) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL11099225 | 0.73 | TACR3 (0.41) | TACR3KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472578-A | Benzo[a]phenazine antimicrobials | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |