Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLR1A | O95602 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096783 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1EGFRSMN1; SMN2CYP1A2 | |
| SCHEMBL11088487 | 0.83 | MEN1 (0.51) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11099295 | 0.81 | TOP2A (0.43) | KDM4ESMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL11090325 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL11079267 | 0.79 | KMT2A (0.40) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10872150 | 0.78 | CSNK2A1 (0.51) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11099225 | 0.77 | TACR3 (0.41) | KDM4EALDH1A1SMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL11099229 | 0.75 | TACR3 (0.38) | KDM4EALDH1A1SMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL9525642 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1EGFRSMN1; SMN2CYP1A2 | |
| SCHEMBL10371855 | 0.75 | RAD52 (0.44) | ALDH1A1EGFRSMN1; SMN2CYP1A2POLR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472578-A | Benzo[a]phenazine antimicrobials | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |