Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370586 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2HTTTSHR | |
| SCHEMBL10369480 | 0.84 | ALDH1A1 (0.35) | KDM4EALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL10370537 | 0.82 | ALDH1A1 (0.46) | KDM4EALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL11079267 | 0.75 | KMT2A (0.40) | KDM4EALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL11099295 | 0.75 | TOP2A (0.43) | KDM4ESMN1; SMN2HTTLMNAMEN1 | |
| SCHEMBL11088487 | 0.74 | MEN1 (0.51) | KDM4EALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL11099229 | 0.74 | TACR3 (0.38) | KDM4EALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL11099232 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL10371855 | 0.72 | RAD52 (0.44) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11090325 | 0.71 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234931-B1 | AZAANTHRACENE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-06-27 | — | — | EP | claimed |