Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695556 | 0.91 | CYP19A1 (0.46) | SCN1ASCN2ASCN3ACYP19A1KMT2A | |
| SCHEMBL6695553 | 0.91 | CYP19A1 (0.46) | SCN1ASCN2ASCN3ACYP19A1KMT2A | |
| SCHEMBL5836880 | 0.91 | CYP19A1 (0.46) | SCN1ASCN2ASCN3ACYP19A1KMT2A | |
| SCHEMBL8071324 | 0.89 | CYP19A1 (0.54) | SCN1ASCN2ASCN3ACYP19A1KMT2A | |
| SCHEMBL11104527 | 0.89 | SCN1A (0.48) | SCN1ASCN2ASCN3AKMT2AMAPT | |
| SCHEMBL9842399 | 0.87 | OXTR (0.42) | SCN1ASCN2ASCN3ACYP19A1KMT2A | |
| SCHEMBL11100739 | 0.87 | SCN1A (0.51) | SCN1ASCN2ASCN3AKMT2AMAPT | |
| SCHEMBL11100553 | 0.87 | HTT (0.46) | SCN1ASCN2ASCN3AKMT2AMAPT | |
| SCHEMBL11106208 | 0.86 | SCN1A (0.50) | SCN1ASCN2ASCN3AKMT2AMAPT | |
| SCHEMBL11102882 | 0.85 | HTT (0.46) | SCN1ASCN2ASCN3AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473487-A | 4-Fluorobiphenyl derivatives, their preparation, and dielectrics and electro-optical display element containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-09-25 | — | — | US | disclosed |