SCHEMBL9842399

SCHEMBL9842399

CC[C@H]1CC[C@H](OC(=O)c2ccc(-c3ccc(F)cc3F)cc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OXTR P30559 1/20 0.42
AVPR1A P37288 1/20 0.42
KMT2A Q03164 2/20 0.42
SCN1A P35498 2/20 0.41
SCN2A Q99250 2/20 0.41
SCN3A Q9NY46 2/20 0.41
CYP19A1 P11511 1/20 0.41
SERPINE1 P05121 1/20 0.40
KLKB1 P03952 2/20 0.40
PTGS2 P35354 1/20 0.39
HTR2A P28223 1/20 0.39
GRM2 Q14416 1/20 0.39
MAOB P27338 1/20 0.39
DHODH Q02127 1/20 0.39
RARB P10826 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
DHFR P00374 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9842448 0.91 OXTR (0.41) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL9842802 0.89 RARB (0.43) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL9842724 0.88 RARB (0.45) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL11099259 0.87 SCN1A (0.50) KMT2ASCN1ASCN2ASCN3ACYP19A1
SCHEMBL9842645 0.87 RARB (0.47) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL9842484 0.86 KMT2A (0.40) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL9842716 0.84 RARB (0.43) KMT2ASCN1ASCN2ASCN3ASERPINE1
SCHEMBL9842249 0.83 RARB (0.47) KMT2ASCN1ASCN2ASCN3ASERPINE1
SCHEMBL8071324 0.83 CYP19A1 (0.54) KMT2ASCN1ASCN2ASCN3ACYP19A1
SCHEMBL6695553 0.82 CYP19A1 (0.46) KMT2ASCN1ASCN2ASCN3ACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413785-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. MERCK PATENT GMBH (DE) 1991-02-27 EP disclosed
WO-1990009420-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed