Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 7/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | GNRHR | P30968 | 2/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.62 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.62 |
| ▸ | CXCL8 | P10145 | 8/20 | 0.61 |
| ▸ | MC4R | P32245 | 1/20 | 0.58 |
| ▸ | MC5R | P33032 | 1/20 | 0.58 |
| ▸ | MC3R | P41968 | 1/20 | 0.58 |
| ▸ | MC1R | Q01726 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093628 | 0.94 | PTGS1 (0.63) | KISS1RABCB11GNRHRCXCL8MC4R | |
| SCHEMBL11199772 | 0.94 | CXCL8 (0.61) | KISS1RABCB11GNRHRDRD1OPRM1 | |
| SCHEMBL11125288 | 0.93 | PTGS1 (0.64) | KISS1RGNRHRDRD1OPRM1MRGPRX2 | |
| SCHEMBL11406923 | 0.93 | KISS1R (0.59) | KISS1RABCB11GNRHRDRD1OPRM1 | |
| SCHEMBL11199733 | 0.91 | KISS1R (0.58) | KISS1RABCB11GNRHRDRD1OPRM1 | |
| SCHEMBL11199735 | 0.91 | CXCR4 (0.59) | KISS1ROPRM1CXCL8MC4RMC5R | |
| SCHEMBL11122441 | 0.91 | KISS1R (0.64) | KISS1RGNRHR | |
| SCHEMBL11270601 | 0.91 | KISS1R (0.64) | KISS1RGNRHR | |
| Acetic Acid SCHEMBL719624 | 0.90 | GNRHR (0.64) | KISS1RABCB11GNRHRDRD1OPRM1 | |
| SCHEMBL16636399 | 0.90 | KISS1R (0.73) | KISS1ROPRM1CXCL8MC4RMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041286-B1 | LH-RH ANTAGONISTS | Schally, Andrew Victor (US) | 1984-08-15 | — | — | EP | claimed |
| US-4317815-A | PEPTIDE ANALOGS OF LUTENIZING HORMONE RELEASING HORMONE | ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND, THE, A CORPORATE ENTITY OF TULANE UNIVERSITY A CORP. OF LA. | 1982-03-02 | — | — | US | claimed |
| EP-0041286-A1 | LH-RH antagonists | Schally, Andrew Victor (US) | 1981-12-09 | — | — | EP | claimed |
| EP-0041286-B1 | LH-RH ANTAGONISTS | Schally, Andrew Victor (US) | 1984-08-15 | — | — | EP | disclosed |
| US-4431635-A | PEPTIDE ANALOGS OF LUTEINIZING HORMONE RELEASING HORMONE; GLANDULAR DISORDERS; ANTICARCINOGENIC AGENTS | COY DAVID HOWARD | 1984-02-14 | — | — | US | disclosed |
| US-4317815-A | PEPTIDE ANALOGS OF LUTENIZING HORMONE RELEASING HORMONE | ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND, THE, A CORPORATE ENTITY OF TULANE UNIVERSITY A CORP. OF LA. | 1982-03-02 | — | — | US | disclosed |
| EP-0041286-A1 | LH-RH antagonists | Schally, Andrew Victor (US) | 1981-12-09 | — | — | EP | disclosed |