Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.34 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665396 | 0.90 | TP53 (0.50) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL9614221 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL11099540 | 0.86 | TP53 (0.58) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL10663763 | 0.86 | TP53 (0.54) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL8200987 | 0.85 | TP53 (0.69) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL10871245 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL9292342 | 0.82 | TP53 (0.58) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL29349823 | 0.81 | TP53 (0.74) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL65705 | 0.81 | TP53 (0.74) | ALDH1A1TP53TDP1CYP3A4MEN1 | |
| SCHEMBL8527963 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TP53TDP1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4602454-A | PLANT SAFENING AGENTS, SEEDS CHLOROACETAMIDE HERBICIDES | MONSANTO COMPANY (US) | 1986-07-29 | — | — | US | claimed |
| US-4602937-A | PLANT SAFENING AGENTS, ACETAMIDE HERBICIDE | MONSANTO COMPANY (US) | 1986-07-29 | — | — | US | claimed |
| US-4586948-A | 2,4-disubstituted-5-thiazole-carboxylic acids and derivatives | MONSANTO COMPANY (US) | 1986-05-06 | — | — | US | claimed |
| US-4437875-A | PLANT SAFENING AGENT FOR ACETAMIDE HERBICIDE | MONSANTO COMPANY (US) | 1984-03-20 | — | — | US | claimed |
| US-4437876-A | PLANT SAFENING AGENTS FOR ACETAMIDE HERBICIDES | MONSANTO COMPANY (US) | 1984-03-20 | — | — | US | claimed |
| EP-0064353-A1 | Use of 2,4-disubstituted-5-thiazolecarboxylic acids and derivatives for reducing injury to crop plants by acetamide herbicides | MONSANTO COMPANY (US) | 1982-11-10 | — | — | EP | claimed |
| US-5321000-A | Benzhydryl compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5162537-A | To safen acetamide herbicids used to control grassy and broadleaf weeds in rice, sorghum and wheat | MONSANTO COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |
| US-4964893-A | REDUCING INJURY TO A CROP PLANT | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4859232-A | Substituted-aryl cyclopropanecarbonitriles and derivatives thereof as herbicide antidotes | MONSANTO COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
| US-4846880-A | 2-(Dichloroacetyl)-3-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | MONSANTO COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| US-4584012-A | PLANT SAFENING AGENTS | MONSANTO COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| US-4437875-A | PLANT SAFENING AGENT FOR ACETAMIDE HERBICIDE | MONSANTO COMPANY (US) | 1984-03-20 | — | — | US | disclosed |
| US-4437876-A | PLANT SAFENING AGENTS FOR ACETAMIDE HERBICIDES | MONSANTO COMPANY (US) | 1984-03-20 | — | — | US | disclosed |
| US-4416687-A | 3,5-Bis (trifluoromethyl)phenoxy carboxylic acids and derivatives thereof | MONSANTO COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0088066-A1 | 3,5-Bis (trifluoromethyl) phenoxy carboxylic acids and derivatives thereof | MONSANTO COMPANY (US) | 1983-09-07 | — | — | EP | disclosed |
| EP-0064353-A1 | Use of 2,4-disubstituted-5-thiazolecarboxylic acids and derivatives for reducing injury to crop plants by acetamide herbicides | MONSANTO COMPANY (US) | 1982-11-10 | — | — | EP | disclosed |
| EP-0064353-A1 | Use of 2,4-disubstituted-5-thiazolecarboxylic acids and derivatives for reducing injury to crop plants by acetamide herbicides | MONSANTO COMPANY (US) | 1982-11-10 | — | — | EP | disclosed |