Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 3/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | RAF1 | P04049 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 2/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584206 | 0.91 | STK39 (0.65) | STK39BRAFKDRMAPK14TNNI3K | |
| SCHEMBL11097485 | 0.85 | TP53 (0.62) | STK39BRAFKDRMAPK14TNNI3K | |
| SCHEMBL8320103 | 0.83 | FFAR1 (0.51) | BRAFKDRMEN1KMT2ACYP1A2 | |
| SCHEMBL11096253 | 0.83 | STK39 (0.51) | STK39BRAFRAF1MEN1KMT2A | |
| SCHEMBL11093171 | 0.83 | STK39 (0.51) | STK39BRAFKDRMAPK14TNNI3K | |
| SCHEMBL11097831 | 0.82 | STK39 (0.50) | STK39MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9054295 | 0.81 | CYP1A2 (0.47) | STK39BRAFRAF1MEN1KMT2A | |
| SCHEMBL8319542 | 0.81 | MAPT (0.48) | BRAFKDRMAPK14TNNI3KMRGPRX4 | |
| SCHEMBL11407116 | 0.81 | MRGPRX4 (0.50) | STK39MEN1KMT2AMRGPRX4CYP1A2 | |
| SCHEMBL10519119 | 0.80 | STK39 (0.48) | STK39MEN1KMT2AEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027965-B1 | SUBSTITUTED UREAS, THEIR PREPARATION AND USE AS HERBICIDES, AND COMPOSITIONS THEREFOR | BASF Aktiengesellschaft (DE) | 1984-06-13 | — | — | EP | claimed |