Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27462059 | 1.00 | BACE1 (0.35) | BACE1FAAHCES1GRIK1GRIK2 | |
| SCHEMBL11110589 | 0.79 | — | — | |
| SCHEMBL22299556 | 0.79 | BACE1 (0.33) | BACE1 | |
| SCHEMBL12654256 | 0.73 | BACE1 (0.34) | BACE1 | |
| SCHEMBL23641103 | 0.73 | BACE1 (0.32) | BACE1 | |
| SCHEMBL10713098 | 0.72 | FAAH (0.31) | FAAHCES1 | |
| SCHEMBL4583970 | 0.70 | FAAH (0.31) | FAAHCES1 | |
| SCHEMBL14047259 | 0.70 | BACE1 (0.31) | BACE1FAAHCES1 | |
| SCHEMBL27424062 | 0.70 | FAAH (0.31) | FAAHCES1 | |
| SCHEMBL14023480 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4429154-A | Fluorinated azomethine compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | claimed |