Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097065 | 0.84 | SLC6A4 (0.48) | SLC6A4SLC6A3 | |
| SCHEMBL11095157 | 0.84 | SLC6A4 (0.48) | SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL11093298 | 0.83 | CHRM2 (0.49) | SLC6A4SLC6A3 | |
| SCHEMBL15248175 | 0.82 | SLC6A3 (0.48) | SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL1011983 | 0.81 | SLC6A4 (0.54) | SLC6A4SLC6A3CYP3A4KDM4EALDH1A1 | |
| SCHEMBL4524255 | 0.81 | SLC6A4 (0.57) | SLC6A4SLC6A3KMT2A | |
| SCHEMBL1011495 | 0.81 | SLC6A4 (0.54) | SLC6A4SLC6A3CYP3A4KDM4EALDH1A1 | |
| SCHEMBL1015012 | 0.81 | SLC6A4 (0.54) | SLC6A4SLC6A3CYP3A4KDM4EALDH1A1 | |
| SCHEMBL15405283 | 0.77 | SLC6A4 (0.54) | SLC6A4SLC6A3CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6121340 | 0.77 | SLC6A4 (0.54) | SLC6A4SLC6A3CYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |