Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015012 | 1.00 | SLC6A4 (0.54) | SLC6A4SLC6A3FKBP1AKMT2AL3MBTL1 | |
| SCHEMBL1012738 | 0.88 | ALDH1A1 (0.46) | SLC6A4SLC6A3KMT2AALDH1A1 | |
| SCHEMBL1012334 | 0.87 | SLC6A4 (0.44) | SLC6A4SLC6A3KMT2AL3MBTL1 | |
| SCHEMBL1010265 | 0.86 | FKBP1A (0.46) | SLC6A4SLC6A3FKBP1A | |
| SCHEMBL7247464 | 0.85 | SLC6A4 (0.43) | SLC6A4SLC6A3KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL1011983 | 0.85 | SLC6A4 (0.54) | SLC6A4SLC6A3FKBP1AKMT2ACYP3A4 | |
| SCHEMBL1011459 | 0.84 | SLC6A4 (0.42) | SLC6A4SLC6A3 | |
| SCHEMBL11099778 | 0.81 | SLC6A4 (0.60) | SLC6A4SLC6A3KMT2ACYP3A4KDM4E | |
| SCHEMBL12530878 | 0.77 | SLC6A3 (0.52) | SLC6A4SLC6A3 | |
| SCHEMBL7652967 | 0.75 | CYP2C19 (0.46) | SLC6A4SLC6A3KMT2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118674-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | NIHON MEDIPHYSICS CO LTD (JP) | 2011-01-05 | — | — | EP | disclosed |