Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574835 | 0.91 | HRH2 (0.55) | HRH2HRH3 | |
| SCHEMBL10661991 | 0.91 | HRH2 (0.57) | HRH2HRH3 | |
| SCHEMBL10744580 | 0.90 | HRH2 (0.53) | HRH2HRH3 | |
| SCHEMBL11268821 | 0.87 | HRH2 (0.54) | HRH2HRH3 | |
| SCHEMBL10401250 | 0.87 | HRH2 (0.54) | HRH2HRH3 | |
| SCHEMBL10667188 | 0.86 | HRH2 (0.53) | HRH2HRH3 | |
| SCHEMBL11263724 | 0.86 | HRH2 (0.53) | HRH2HRH3 | |
| SCHEMBL11271145 | 0.86 | HRH2 (0.52) | HRH2HRH3 | |
| SCHEMBL11263720 | 0.85 | HRH2 (0.52) | HRH2HRH3 | |
| SCHEMBL10401022 | 0.85 | HRH2 (0.53) | HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016565-B1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1984-05-23 | — | — | EP | disclosed |