Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401250 | 1.00 | HRH2 (0.54) | HRH2HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL10667188 | 0.99 | HRH2 (0.53) | HRH2HRH3 | |
| SCHEMBL11263724 | 0.99 | HRH2 (0.53) | HRH2HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL11271145 | 0.99 | HRH2 (0.52) | HRH2HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL11263720 | 0.97 | HRH2 (0.52) | HRH2HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL9574835 | 0.96 | HRH2 (0.55) | HRH2HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL10744580 | 0.95 | HRH2 (0.53) | HRH2HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL10401022 | 0.92 | HRH2 (0.53) | HRH2HRH3TP53CYP1A2CYP3A4 | |
| SCHEMBL11100387 | 0.87 | HRH2 (0.50) | HRH2HRH3 | |
| SCHEMBL10400338 | 0.84 | SMN1; SMN2 (0.51) | HRH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050407-A1 | 3,5-Disubstituted-1,2,4-triazole compounds, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1982-04-28 | — | — | EP | disclosed |