Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 4/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9180938 | 0.85 | GAA (0.56) | MAPTGAALMNAHTTHPGD | |
| SCHEMBL3152806 | 0.85 | MAPT (0.49) | MAPTGAALMNAHTTHPGD | |
| SCHEMBL12258259 | 0.82 | CYP1A2 (0.55) | MAPTGAALMNAHTTHPGD | |
| SCHEMBL5405587 | 0.81 | MAPT (0.41) | MAPTGAALMNAHTTHPGD | |
| SCHEMBL4788222 | 0.81 | PARP1 (0.46) | MAPTGAALMNAHPGDKDM4E | |
| SCHEMBL2910077 | 0.78 | DHODH (0.46) | MAPTGAALMNAHTTHPGD | |
| SCHEMBL10250830 | 0.77 | NCF1 (0.56) | MAPTGAALMNAHTTHPGD | |
| SCHEMBL8685809 | 0.74 | KDM4E (0.38) | MAPTGAALMNAHTTHPGD | |
| SCHEMBL17866953 | 0.74 | ELANE (0.44) | MAPTGAALMNAHTTHPGD | |
| SCHEMBL480946 | 0.74 | ELANE (0.44) | MAPTGAALMNAHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113432-A1 | Chloromethyl quinoline derivatives, process for their preparation and their use | ALKALOIDA VEGYéSZETI GYáR (HU) | 1984-07-18 | — | — | EP | disclosed |