Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30592750 | 0.83 | KDM4E (0.44) | KDM4ELMNAMAPTGAAALDH1A1 | |
| SCHEMBL3333058 | 0.77 | IGFBP3 (0.47) | KDM4EMAPTALDH1A1ELANETDP1 | |
| SCHEMBL439466 | 0.76 | NCF1 (0.44) | KDM4ELMNAMAPTGAAALDH1A1 | |
| SCHEMBL8686911 | 0.76 | LMNA (0.47) | KDM4ELMNAMAPTGAAALDH1A1 | |
| SCHEMBL8872898 | 0.76 | KDM4E (0.42) | KDM4ELMNAMAPTGAAALDH1A1 | |
| SCHEMBL11100714 | 0.74 | MAPT (0.49) | KDM4ELMNAMAPTGAAALDH1A1 | |
| SCHEMBL9180938 | 0.71 | GAA (0.56) | KDM4ELMNAMAPTGAAALDH1A1 | |
| SCHEMBL30666580 | 0.71 | TDP1 (0.39) | KDM4ELMNAMAPTGAAALDH1A1 | |
| SCHEMBL15031914 | 0.71 | TDP1 (0.39) | KDM4ELMNAMAPTGAAALDH1A1 | |
| SCHEMBL28842256 | 0.69 | POLB (0.41) | LMNAMAPTALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756517-A | BACTERICIDES AND BRAIN DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |