Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111880 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAHTTHTR1AGALR3 | |
| SCHEMBL11102905 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAHTTHTR1AL3MBTL1 | |
| SCHEMBL11288219 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAHTTHTR1AGALR3 | |
| SCHEMBL11109296 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAHTTHTR1AL3MBTL1 | |
| SCHEMBL11106347 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAHTTHTR1AGALR3 | |
| SCHEMBL11104840 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAHTTHTR1AL3MBTL1 | |
| SCHEMBL11110999 | 0.81 | KDM4E (0.46) | SMN1; SMN2LMNAHTTKMT2AS1PR4 | |
| SCHEMBL11103158 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAHTTHTR1AL3MBTL1 | |
| SCHEMBL11289412 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAHTTHTR1AGALR3 | |
| SCHEMBL9221645 | 0.78 | HTR1A (0.41) | SMN1; SMN2LMNAHTTHTR1AGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |